Meeting the societal effects of demographic change, globalization, digitization and growing social inequality requires collective action on the part of government, civil society and the private sector. But what do businesses offer in developing effective solutions to the challenges we face as a society? The Bertelsmann Stiftung conducted global research on this question for the Reinhard Mohn Prize 2016. The findings presented here are accompanied by contributions from experts on the role of business and entrepreneurship in society. They examine how businesses are integrated into international networks and how they help advance society through social innovations. As a contribution to debates on these issues, this volume offers recommendations for a blueprint of responsible entrepreneurship and a policy framework designed to promote it.